57Co-bleomycin and 67Ga-citrate in detecting and staging lung cancer.
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چکیده
منابع مشابه
57Co-bleomycin and 67Ga-citrate in detecting and staging lung cancer.
In the investigation of suspected lung cancer bleomycin labelled with cobalt-57 and gallium-67 labelled with citrate are currently used to detect the primary tumour and to establish the presence of metastases in the lung hilum and mediastinum. A comparative study of these radio-pharmaceuticals was performed in 63 patients with proved lung cancer. 57Co-bleomycin showed the primary tumour in 58 p...
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67Gallium-bleomycin complex (67Ga-BLM) was prepared using Thakour method. Radio-thin-layer-chromatography of prepared complex showed A2 and B2 radiopeaks with Rf at 0.7 and 0.4 respectively with a purity of above % 95. Tissue uptake of 67Ga-BLM and 67GaCl3 in twelve tissues including tumor, blood, liver, lung, spleen, muscle, skin, heart, kidney, colon, colon content ,bladder and the tota...
متن کاملA comparison of cobalt (57Co) bleomycin scanning and contrast-enhanced CT scanning for assessment of the mediastinum in lung cancer.
Sixty patients with histologically proven lung cancer who had been accepted for mediastinoscopy or thoracotomy were prospectively entered into a study to evaluate computed tomographic (CT) scanning, 57Co-bleomycin scanning, and barium swallow in preoperative assessment of mediastinal lymph node metastasis. Fifty-six patients had thoracotomy at which all accessible lymph nodes were sampled. Twen...
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This study reports the labeling of Gallium-Bleomycin (67Ga-BLM) complex as a radiopharmaceutical and optimization of its labeling conditions; pH, reaction time, temperature, concentration of bleomycin and its biodistribution in normal Bulb C mice. The biodistribution of the complex was compared with 67Ga-Cl3 in 11 selected organs including blood, liver, lung, spleen, muscle, skin, heart, kidney...
متن کامل[Molecular staging and prognosis in lung cancer].
The term “molecular staging” has been used to refer to the determination of tumor markers in the lymph tissue as an indicator of the presence of neoplastic cells. It is known that there are often minimal tumor cell foci or micrometastases (diameter less than 2 mm) which may be missed in the histopathological examination and that are usually only detectable by immunohistochemistry. Recently, new...
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ژورنال
عنوان ژورنال: Thorax
سال: 1983
ISSN: 0040-6376
DOI: 10.1136/thx.38.1.16